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IL33 Antibody

IL33 Antibody

Item no.	OAPB00547
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Neuroscience Neural Lineage Markers Neuroinflammation Metabolism Diabetes Glucose Homeostasis Molecular Targets for Neuroscience Neural Signaling Antibodies Cell Biology Cell Culture Cytokines Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining Neurodegeneration Markers Glial Cell Markers Neuronal Cell Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	Schmitz J, Owyang A, Oldham E, et al. IL-33, and interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity2005; 23:479-90.; Dinarello CA. Interleukin-18, a proinflammatory cytokine. Eur. Cytokine Netw.2000; 11:483-6.; Brint EK, Xu D, Liu H, et al. ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance. Nat. Immunol.2004; 5:373-9.; Chackerian AA, Oldham ER, Murphy EE, et al. IL-1 receptor accessory protein and ST2 comprise the IL-33 receptor complex. J. Immunol.2007; 179:2551-5.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C9orf26;DVS27;DVS27-related protein;IL1F11;interleukin-1 family member 11;interleukin-33;NFEHEV;NF-HEV;nuclear factor for high endothelial venules;nuclear factor from high endothelial venules.
Similar products	IL-33
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	Predicted: 31kD Observed: 33kD
Manufacturer - Application Additional Information	IL-33 antibody can be used for the detection of IL-33 by Western blot at 1 - 2 ug/mL. Observed: 35 kDa For immunofluorescence start at 20 g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 g/mL.
Gene symbol	IL33
Gene Fullname	interleukin 33
Product format	Liquid. IL-33 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	IL-33 antibody can be stored at 4C for three months and -20C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Cytokine that binds to and signals through the IL1RL1/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed:16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an "alarmin", that amplifies immune responses during tissue injury (PubMed:17853410, PubMed:18836528).
Nucleotide accession_num	NM_001199640.1; NM_001199641.1; NM_033439.3; XM_005251626.3; XM_005251627.1
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_254274
Protein name	Interleukin-33\|interleukin-33 isoform a precursor [Homo sapiens]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Anti-IL-33 antibody (4273) was raised against a 17 amino acid synthetic peptide from near the center of human IL-33. The immunogen is located within the 150-200 amino acids of IL-33.
Homology	Human; Mouse; Rat
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 11/27/2025

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