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CUEDC2 Antibody

CUEDC2 Antibody

Item no.	OAPB00767
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Oncology Food Safety Hormones Antibodies By Cell Type Carcinoma Sarcoma Western Blot ELISA Immunocytochemistry Primary Antibodies By Organ Breast Cancer Immunostaining Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Cattle (Bovine)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Shih SC, Prag G, Francis SA, et al. A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. EMBO J.2003; 22:1273-81.;Ponting CP. Proteins of the endoplasmic-reticulum-associated degradation pathway: domain detection and function prediction. Biochem. J.2000; 351:527-35.;Prag G, Misra S, Jones EA, et al. Mechanism of ubiquitin recognition by the CUE domain of Vps9p. Cell2003; 113:609-20.;Kang RS, Daniels CM, Francis SA, et al. Solution structure of a CUE-ubiquitin complex reveals a conserved mode of ubiquitin binding. Cell2003; 113:621-30.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	bA18I14.5;C10orf66;CUE domain-containing protein 2.
Similar products	CUEDC2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	Predicted: 32 kDa Observed: 34 kDa
Manufacturer - Application Additional Information	CUEDC2 antibody can be used for detection of CUEDC2 by Western blot at 1 - 2 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	CUEDC2
Gene Fullname	CUE domain containing 2
Product format	Liquid. CUEDC2 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	CUEDC2 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism.
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_076945
Protein name	CUE domain-containing protein 2\|CUE domain-containing protein 2 [Homo sapiens]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	CUEDC2 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human CUEDC2. The immunogen is located within the last 50 amino acids of CUEDC2.
Homology	Human; Mouse; Rat
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 10/30/2025

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