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SIPA1L1 Antibody

SIPA1L1 Antibody

Item no.	OAPB00996
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Food Safety Allergenes Neuroscience Molecular Targets for Neuroscience Neural Signaling Antibodies Cell Biology Cytoskeleton Immunohistochemistry Western Blot ELISA Immunofluorescence Primary Antibodies Immunostaining small GTPases Ras Subfamily Rap Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Minato N and Hattori M. SPA-1 (Sipa1) and Rap signaling in leukemia and cancer metastasis. Cancer Sci.2009; 100:17-23.;Gao Q, Srinivasan S, Boyer SN, et al. The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation. Mol. Cell Biol.1999; 19:733-44.;Tsai I-C, Amack JD, Gao Z-H, et al. A Wnt-CKI e-Rap1 pathway regulates gastrulation by modulating SIPA1L1, a Rap GTPase activating protein. Dev. Cell2007; 12:335-47.;
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E6TP1;high-risk human papilloma viruses E6 oncoproteins targeted protein 1;signal-induced proliferation-associated 1-like protein 1;SIPA1-like protein 1;SPAR1;spine-associated RapGAP 1.
Similar products	SIPA1L1
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	SIPA1L1 antibody can be used for detection of SIPA1L1 by Western blot at 0.5 - 1 ug/ml. (Optimal dilution should be determined by user)
Gene symbol	SIPA1L1
Gene Fullname	signal induced proliferation associated 1 like 1
Product format	Liquid. SIPA1L1 Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	SIPA1L1 antibody can be stored at 4C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Stimulates the GTPase activity of RAP2A. Promotes reorganization of the actin cytoskeleton and recruits DLG4 to F-actin. Contributes to the regulation of dendritic spine morphogenesis (By similarity).
Nucleotide accession_num	NM_001284245.1; NM_001284246.1; NM_001284247.1; NM_015556.2; XM_005267516.3; XM_005267519.1
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/NP_056371
Protein name	Signal-induced proliferation-associated 1-like protein 1\|signal-induced proliferation-associated 1-like protein 1 isoform 1 [Homo sapiens]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	SIPA1L1 antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SIPA1L1. The immunogen is located within amino acids 40 - 90 of SIPA1L1.
Homology	Human; Mouse; Rat
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 12/25/2025

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