BCL6 Antibody - C-terminal region

Root Catalog/Products/Primary Antibodies, Root Catalog/Research Areas/Cancer/Cancer Signal Transduction, Root Catalog/Research Areas/Cancer/Cancer Transcription Factor

Wet Ice

WB: 1:100~250

Liquid PBS with 0.09% (W/V) sodium azide.

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

B-cell lymphoma 6 protein

This antibody is purified through a protein G column, followed by dialysis against PBS.

Approximately 0.5mg/ml. Actual concentration varies with each lot.