MITF Antibody - N-terminal region

Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Research Areas/Cancer/Cancer Transcription Factor

Wet Ice

WB: 1:2000
WB: 1:1000
IF: 1:10~50
FC: 1:10~50

Liquid. PBS with 0.09% (W/V) sodium azide.

This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Microphthalmia-associated transcription factor

This antibody is purified through a protein A column, followed by peptide affinity purification.

Human; Mouse