« Back
Home /
H2AFX Antibody - C-terminal region (OAAB17707)

H2AFX Antibody - C-terminal region (OAAB17707)

Item no.	OAAB17707
Manufacturer	AVIVA Systems Biology
Amount	200ul
Category	Neuroscience Neural Epigenetics Antibodies Western Blot Primary Antibodies
Type	Antibody Monoclonal
Format	Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Applications	WB
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	H2AFX, H2AX, Histone H2A.x
Similar products	H2AFX, H2AX, Histone H2A.x
Available
Gene symbol	H2AFX
Molecular weight	15 kDa
Product format	Liquid. Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Gene id	3014
Reconstitution and storage	Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target	Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Purification	This antibody is purified through a protein G column, followed by dialysis against PBS.
Clonality	Monoclonal
Immunogen	This H2AFX antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 115-143 amino acids from the C-terminal region of human H2AFX.
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OAAB17707-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 200ul

available

Delivery expected until 9/25/2025

Compare

Add to wishlist

Get an offer

Request delivery time