Comparison

CTNNB1 Antibody - C-terminal region (OAAB18612)

Item no. OAAB18612
Manufacturer AVIVA Systems Biology
Amount 400 ul
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, FC, IF, IHC
Specific against Human (Homo sapiens)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CTNNB1,CTNNB,Catenin beta-1,Beta-catenin
Similar products Catenin beta-1, CTNNB1, CTNNB, Beta-catenin
Shipping Condition Cool pack
Available
Shipping Temperature
Wet Ice
Molecular Weight
85 kDa, 86 kDa
Gene symbol
CTNNB1
Product format
Liquid. Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Reconstitution and storage
Maintain refrigerated at 2-8C for up to 2 weeks. For long term storage store at -20C in small aliquots to prevent freeze-thaw cycles.
Description of target
The protein encoded by this gene is part of a complex of
proteins that constitute adherens junctions (AJs). AJs are
necessary for the creation and maintenance of epithelial cell
layers by regulating cell growth and adhesion between cells. The
encoded protein also anchors the actin cytoskeleton and may be
responsible for transmitting the contact inhibition signal that
causes cells to stop dividing once the epithelial sheet is
complete. Finally, this protein binds to the product of the APC
gene, which is mutated in adenomatous polyposis of the colon.
Mutations in this gene are a cause of colorectal cancer (CRC),
pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer.
Three transcript variants encoding the same protein have been found
for this gene.
Clonality
Polyclonal
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CTNNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human CTNNB1.
Homology
Cow; Mouse; Rat

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
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