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MAD1L1 Antibody

MAD1L1 Antibody

Item no.	OAAF01143
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Astrocytoma By Organ Bladder Cancer Immunostaining Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Jin D.-Y., Cell 93:81-91(1998). Hillier L.W., Nature 424:157-164(2003). Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	MAD1;MAD1 mitotic arrest deficient like 1;MAD1-like protein 1;mitotic arrest deficient 1-like protein 1;mitotic checkpoint MAD1 protein homolog;mitotic spindle assembly checkpoint protein MAD1;mitotic-arrest deficient 1,yeast,homolog-like 1;PIG9;tax-binding protein 181;TP53I9;tumor protein p53 inducible protein 9;TXBP181.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	83 kDa
Manufacturer - Application Additional Information	IF: 1:100~1:500; ELISA: 1:1000
Gene symbol	MAD1L1
Gene Fullname	mitotic arrest deficient 1 like 1
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Component of the spindle-assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. May recruit MAD2L1 to unattached kinetochores. Has a role in the correct positioning of the septum. Required for anchoring MAD2L1 to the nuclear periphery. Binds to the TERT promoter and represses telomerase expression, possibly by interfering with MYC binding.
Protein accession_num	NP_001013858.1
Protein name	Mitotic spindle assembly checkpoint protein MAD1
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human MAD1.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	MAD1 antibody detects endogenous levels of total MAD1 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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