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RapGEF1 Antibody

RapGEF1 Antibody

Item no.	OAAF01157
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Targets for Rodent Neurosciences Neural Signaling Antibodies By Cell Type Carcinoma Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Tanaka S., Proc. Natl. Acad. Sci. U.S.A. 91:3443-3447(1994). Knudsen B., J. Biol. Chem. 269:32781-32787(1994). Humphray S.J., Nature 429:369-374(2004).
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	C3G;CRK SH3-binding GNRP;GRF2;Guanine nucleotide-releasing factor 2;guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene);Protein C3G;Rap guanine nucleotide exchange factor (GEF) 1;rap guanine nucleotide exchange factor 1.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	120 kDa
Manufacturer - Application Additional Information	IHC: 1:50~1:100; ELISA: 1:1000
Gene symbol	RAPGEF1
Gene Fullname	Rap guanine nucleotide exchange factor 1
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.
Protein accession_num	NP_005303.2
Protein name	Rap guanine nucleotide exchange factor 1
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human RAPGEF1.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	RapGEF1 antibody detects endogenous levels of total RapGEF1 protein
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/13/2025

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