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CASP10 Antibody

CASP10 Antibody

Item no.	OAAF01739
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Melanoma Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot ELISA Immunofluorescence Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC, ICC, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Citations	Frank C. Kischkel, J. Biol. Chem., Nov 2001; 276: 46639 - 46646. Ingo H. Engels, Mol. Cell. Biol., Apr 2005; 25: 2808 - 2818. Daniela Sciaky, J. Immunol., Apr 2000; 164: 3806. Jin Wang, PNAS, Nov 2001; 98: 13884.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	ALPS2;apoptotic protease MCH-4;CASP-10;caspase 10 apoptosis-related cysteine peptidase;caspase 10,apoptosis-related cysteine protease;caspase-10;FADD-like ICE2;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;FLICE-2;ICE-like apoptotic protease 4;interleukin-1B-converting enzyme 2;MCH4.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Applications	Enzyme-linked immunosorbent assay\|Immunocytochemistry\|Immunofluorescence\|Immunohistochemistry\|Immunohistochemistry-Paraffin\|Western blot
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Molecular Weight	58 kDa
Manufacturer - Application Additional Information	WB: 1:300~1:1000; IHC: 1:50~1:100; IF: 1:100~1:500; ELISA: 1:10000
Gene symbol	CASP10
Gene Fullname	caspase 10
Product format	Liquid
Reconstitution and storage	-20°C
Description of target	Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase-3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-\|-AMC and Asp-Glu-Val-Asp-\|-AMC.
Protein accession_num	NP_001193453.1
Protein name	Caspase-10
Clonality	Polyclonal
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen	The antiserum was produced against synthesized peptide derived from human Caspase 10.
Dilution	The optimal working dilution should be determined by the end user.
Manufacturer - Specificity	Caspase 10 antibody detects endogenous levels of total Caspase 10 protein.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 1/29/2026

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