Comparison

PTGS1 Antibody

Item no. OAAF01762
Manufacturer AVIVA Systems Biology
Amount 100 ug
Category
Type Antibody Polyclonal
Format Liquid
Applications WB, IF, IHC, ELISA
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Citations Lawrence M. Szewczuk, J. Biol. Chem., May 2004; 279: 22727 - 22737.
Syed R. Baber, Am J Physiol Heart Circ Physiol, Oct 2005; 289: H1476 - H1487.
Subhashini Chandrasekharan, J. Lipid Res., Dec 2005; 46: 2636 - 2648.
K. Trent Moreland, J. Pharm
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias COX1;COX3;cyclooxygenase-1;PCOX1;PES-1;PGG/HS;PGH synthase 1;PGHS1;PGHS-1;PHS1;prostaglandin G/H synthase 1;prostaglandin H2 synthase 1;Prostaglandin-endoperoxide synthase 1;prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase);PTGHS.
Shipping Condition Cool pack
Available
Manufacturer - Type
Polyclonal Antibody
Manufacturer - Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Manufacturer - Category
Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature
Wet Ice
Molecular Weight
68 kDa
Manufacturer - Application Additional Information
WB: 1:500~1:3000; IHC: 1:50~1:100; ELISA: 1:40000
Gene symbol
PTGS1
Gene Fullname
prostaglandin-endoperoxide synthase 1
Product format
Liquid
Reconstitution and storage
-20°C
Description of target
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells.
Protein accession_num
NP_000953.2
Protein name
Prostaglandin G/H synthase 1
Clonality
Polyclonal
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized peptide derived from human Cox1.
Dilution
The optimal working dilution should be determined by the end user.
Manufacturer - Specificity
COX1 antibody detects endogenous levels of total COX1 protein.
Formulation
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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