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Anti-LRRK2 Antibody (OAAI00594)

Anti-LRRK2 Antibody (OAAI00594)

Item no.	OAAI00594
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Neuroscience Neural Lineage Markers Neuroinflammation Neural Mitochondrial Function Neural Transcription Factors Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding Antibodies Cell Biology Cell Status Immunohistochemistry Immunoprecipitation Western Blot ELISA Autophagy Primary Antibodies Immunostaining Glial Cell Markers
Type	Antibody Polyclonal
Applications	WB, IP, IHC, ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG kappa
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	PARK8,RIPK7,ROCO2,AURA17,DARDARIN
Similar products	PARK8, AURA17, DARDARIN, RIPK7, ROCO2
Available
Manufacturer - Applications	Positive Control: LRRK2 Transfected HEK-293 Cell Lysate Western Blot: 0.1-1 &mu, g/ml ELISA: 0.01-0.1 &mu, g/ml IP: 2-5 &mu, g/ml IHC: Not tested
Molecular Weight	285 kDa
Gene symbol	LRRK2
Reconstitution and storage	The antibodies are stable for 12 months from date of receipt when stored at -20°, C to -70°, C. The antibodies can be stored at 2°, C to 8°, C for three month without detectable loss of activity.Avoid repeated freezing thawing cycles.
Description of target	The leucine-rich repeat kinase family (LRKK) proteins are consists of an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40. Various genes and loci (&alpha, -synuclein/PARK1 and 4, parkin/PARK2, UCH-L1/PARK5, PINK1/PARK6, DJ-1/PARK7, LRRK2/PARK8, synphilin-1 and NR4A2) are associated to Parkinson's Disease (PD). LRRK2 may play an important role as a therapeutic target for treatment of PD (5).
Purification	The Rabbit IgG is purified by Epitope Affinity Purification.
Immunogen	A synthetic peptide corresponding to C-terminus of Human LRRK2.
Manufacturer - Specificity	This antibody recognizes ca.285 kDa of Human LRRK2 protein. The other species are not tested

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/11/2025

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