« Back
Home /
MCAM Antibody - Biotin Conjugated

MCAM Antibody - Biotin Conjugated

Item no.	OACA01707
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Lymphoma Myeloma Western Blot ELISA Primary Antibodies By Organ Skin Cancer Immunostaining Adhesion Molecule Markers
Type	Antibody Polyclonal
Format	Liquid
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Biotin
Purity	Caprylic Acid Ammonium Sulfate Precipitation purified
Citations	[1] MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily.Lehmann J.M., Riethmueller G., Johnson J.P.Proc. Natl. Acad. Sci. U.S.A. 86:9891-9895(1989) [2] Genomic organization of the melanoma-associated glycoprotein MUC18: implications for the evolution of the immunoglobulin domains.Sers C., Kirsch K., Rothbaecher U., Riethmueller G., Johnson J.P.Proc. Natl. Acad. Sci. U.S.A. 90:8514-8518(1993) [3] Identification and functional assessment of endothelial P1H12.Solovey A.N., Gui L., Chang L., Enenstein J., Browne P.V., Hebbel R.P.J. Lab. Clin. Med. 138:322-331(2001)
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD146;cell surface glycoprotein MUC18;cell surface glycoprotein P1H12;Gicerin;HEMCAM;melanoma adhesion molecule;Melanoma cell adhesion molecule;melanoma-associated antigen A32;melanoma-associated antigen MUC18;MelCAM;METCAM;MUC18;S-endo 1 endothelial-associated antigen.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Gene symbol	MCAM
Gene Fullname	melanoma cell adhesion molecule
Product format	Liquid
Reconstitution and storage	-20°C or -80°C
Description of target	Plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. Could be an adhesion molecule active in neural crest cells during embryonic development. Acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2/FAK1, and a transient increase in the intracellular calcium concentration.
Nucleotide accession_num	NM_006500.2
Protein accession_num	NP_006491.2
Protein name	Cell surface glycoprotein MUC18
Clonality	Polyclonal
Purification	Protein G Purified
Immunogen	Recombinant Human Cell surface glycoprotein MUC18 protein (50-646AA)
Storage Buffer	Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OACA01707-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ug

available

Delivery expected until 10/30/2025

Express Delivery: Save 2 days

Compare

Add to wishlist

Get an offer