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Anti-SARM (human) (Sarmy-1) Antibody

Anti-SARM (human) (Sarmy-1) Antibody

Item no.	OAED00366
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Neuroscience Neural Lineage Markers Neural Adhesion Molecules Antibodies By Cell Type Blastoma Carcinoma Hematology Leukemia Lymphoma Adenocarcinoma Immunoprecipitation Primary Antibodies By Organ Bladder Cancer Glial Cell Markers
Type	Antibody Monoclonal
Format	Liquid
Applications	IP
Clone	Sarmy-1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	hSARM1;HsTIR;MyD88-5;NAD(+) hydrolase SARM1;NADase SARM1;NADP(+) hydrolase SARM1;SAM domain-containing protein 2;SAMD2;SARM;sterile alpha and Armadillo repeat protein;sterile alpha and HEAT/Armadillo motif protein,ortholog of Drosophila;sterile alpha and TIR motif-containing protein 1;sterile alpha motif domain-containing protein 2;tir-1 homolog.
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	IP: 1:200 Does not work for Western Blot. Optimal dilutions/applications should be determined by the end user.
Gene symbol	SARM1
Gene Fullname	sterile alpha and TIR motif containing 1
Product format	Liquid PBS with 10% glycerol and 0.02% sodium azide
Reconstitution and storage	Store short-term at 4°C and long-term at -20°C. Stable for at least 1 year after receipt when stored at -20°C. Avoid freeze/thaw cycles.
Description of target	Negative regulator of MYD88- and TRIF-dependent toll-like receptor signaling pathway which plays a pivotal role in activating axonal degeneration following injury. Promotes Wallerian degeneration an injury-induced axonal death pathway which involves degeneration of an axon distal to the injury site. Can activate neuronal death in response to stress. Regulates dendritic arborization through the MAPK4-JNK pathway. Involved in innate immune response. Inhibits both TICAM1/TRIF- and MYD88-dependent activation of JUN/AP-1, TRIF-dependent activation of NF-kappa-B and IRF3, and the phosphorylation of MAPK14/p38.
Protein name	Sterile alpha and TIR motif-containing protein 1
Clonality	Monoclonal
Purification	Purified from concentrated hybridoma tissue culture supernatant
Immunogen	Recombinant human SARM (aa 93-292).
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 11/27/2025

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