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Anti-TIGAR (human) (Woody-1) Antibody (OAED00396)

Anti-TIGAR (human) (Woody-1) Antibody (OAED00396)

Item no.	OAED00396
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Adenocarcinoma Immunoprecipitation Western Blot Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies Astrocytoma By Organ Breast Cancer
Type	Antibody Monoclonal
Applications	WB, IP
Clone	Woody-1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG2b
Purity	Protein G-affinity purified.<br/>a‰¥95% (SDS-PAGE)
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	TP53-induced glycolysis and apoptosis regulator
Shipping Condition	Cool pack
Available
Shipping Temperature	Wet Ice
Gene symbol	TIGAR
Reconstitution and storage	Long Term Storage : -20C Short Term Storage : +4C Handling : After opening, prepare aliquots and store at -20C. Avoid freeze/thaw cycles. Stable for at least 1 year after receipt when stored at -20C.
Description of target	The p53 tumor-suppressor protein prevents cancer development through various mechanisms, including the induction of cell-cycle arrest, apoptosis, and the maintenance of genome stability. TIGAR (TP53-induced glycolysis and apoptosis regulator) has been identified as a p53-inducible gene. TIGAR expression decreased fructose-2, 6-bisphosphate levels in cells, resulting in an inhibition of glycolysis. In addition, TIGAR expression lowered intracellular reactive oxygen species (ROS) levels and protected cells from p53-induced apoptosis. Bensaad et al., proposed that TIGAR modulates the apoptotic response to p53, thereby allowing cells to survive mild or transient stress.
Protein name	Fructose-2, 6-bisphosphatase TIGAR
Clonality	Monoclonal
Immunogen	Recombinant humanA TIGAR (aa 1-270).
Formulation	Liquid. In PBS containing 0.02% sodium azide.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ug

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Delivery expected until 12/25/2025

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