C3 Antibody

Enzyme-linked immunosorbent assay|Immunohistochemistry-Frozen|Western blot

Immunohistology - Frozen:    1/10

1663

-20°C

NP_000055.2

Monoclonal

Human complement component C3.

Mouse anti Human C3a antibody, clone H13 recognizes human C3a anaphylatoxin, a cleavage product of human complement component C3. C3a increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
Mouse anti Human C3a antibody, clone H13 recognizes a C3a-determinant also present on native C3. Mouse anti Human C3a antibody, clone H13 allows discrimination of ubiquitous or non-specifically bound native C3 or C3a from biologically active C3b fragment, neither C3b or C5 components are recognized by Mouse anti Human C3a antibody, clone H13 (Burger et al. 1987).
Mouse anti Human C3a antibody, clone H13 is reported to block C3a functional activity (Hartmann et al. 1997).