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INS Antibody (OASA02647)

INS Antibody (OASA02647)

Item no.	OASA02647
Manufacturer	AVIVA Systems Biology
Amount	0.2mg
Category	Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite Antibodies ELISA Endocrine Regulation of Lipid Metabolism Primary Antibodies
Type	Antibody Monoclonal
Format	Purified IgG - liquid
Applications	ELISA
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	ILPR, IRDN, IDDM2, MODY10, INS
Similar products	INS
Available
Gene symbol	INS
Protein name	Insulin
Protein size	110
Product format	Liquid PBS with 0.09% sodium azide
Gene id	3630
Reconstitution and storage	Store at 4C or at -20C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
Description of target	C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca²⁺ concentration and subsequent stimulation of N⁺, K⁺-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Levels of C-peptide can be used to distinguish between type 1 and type 2 diabetes. Patients with type 1 diabetes usually have decreased levels of C-peptide, while patients with type 2 diabetes will have normal or higher than normal levels.
Purification	Affinity chromatography on Protein A from tissue culture supernatant.
Clonality	Monoclonal
Warning	This product contains sodium azide, which forms hydrazoic acid under acidic conditions and may react with lead or copper plumbing to produce explosive metal azides. On disposal, flush with large amounts of water to prevent accumulation.
Immunogen	Recombinant human proinsulin
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

OASA02647-datasheet.pdf

OASA02647-safety-datasheet.pdf