« Back
Home /
TFRC Antibody - N-terminal region

TFRC Antibody - N-terminal region

Item no.	ARP63719_P050
Manufacturer	AVIVA Systems Biology
Amount	100 ul
Category	Oncology Neuroscience Aging & Neurological Disorders Antibodies By Cell Type Hematology Leukemia Immunohistochemistry Western Blot Primary Antibodies By Organ Breast Cancer
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IHC
Specific against	Human (Homo sapiens), Rabbit (Oryctolagus cuniculus)
Host	Rabbit
Sequence	PVREEPGEDFPAARRLYWDDLKRKLSEKLDSTDFTGTIKLLNENSYVPRE
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	T9,TR,TFR,p90,CD71,TFR1,TRFR,IMD46
Similar products	TFRC
Shipping Condition	Cool pack
Available
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Research Areas/Hypoxia, Root Catalog/Products/Polyclonal Antibodies/Trial Size Polyclonal Antibodies, Root Catalog/Products/Primary Antibodies, Root Catalog/Products/Aviva Rabbit Polyclonal
Shipping Temperature	Wet Ice
Molecular Weight	84kDa
Species Tested	Human
Gene symbol	TFRC
Gene Fullname	Transferrin receptor (p90, CD71)
Protein size	760
Product format	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution and storage	For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
Partner proteins	HUWE1; UBC; SGTA; CAV1; TP53; RAB8A; RANBP9; LGR4; MDM2; RPA3; RPA2; RPA1; ASB4; RNF2; OPTN; ADRB2; CLN3; MARCH8; env; MARCH1; MYO1G; VCAM1; ITGA4; FN1; ATF2; B4GALT1; ESR1; ATP6V1B1; FBXO6; KCNA5; KCNA3; vpu; SH3BP4; PARK2; LAPTM4B; LAPTM4A; HGS; SUMO2;
Description of target	TFRC is a cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system By similarity. A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
Nucleotide accession_num	NM_003234
Protein accession_num	NP_003225
Protein name	Transferrin receptor protein 1
Clonality	Polyclonal
Purification	Affinity Purified
Homology	Human: 100%; Rabbit: 91%
Concentration	0.5 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 100 ul

available

Delivery expected until 11/13/2025

Express Delivery: Save 3 days

Compare

Add to wishlist

Get an offer