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CD74 Antibody

CD74 Antibody

Item no.	OAEE00498
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg (C100)
Category	Oncology Antibodies By Cell Type Carcinoma Melanoma Adenocarcinoma Flow Cytometry Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies Functional Assays
Type	Antibody Monoclonal
Applications	WB, FC, IP, IHC, FA
Clone	M5/114
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2b
Purity	> 95% (SDS-PAGE)
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	II,p33,DHLAG,HLADG,Ia-GAMMA
Similar products	MHC Class II
Shipping Condition	Cool pack
Available
Manufacturer - Type	Monoclonal Antibody
Manufacturer - Applications	Flow cytometry\|Functional assay\|Immunohistochemistry-Frozen\|Immunohistochemistry-Paraffin\|Immunoprecipitation\|Western blot
Manufacturer - Category	Root Catalog/Products/Monoclonal Antibodies, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	FC: 2 ug/mL
Gene symbol	CD74
Gene Fullname	HLA class II histocompatibility antigen gamma chain
Product format	Phosphate buffered saline (PBS), pH 7.4
Reconstitution and storage	2°C to 8°C
Description of target	MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.
Nucleotide accession_num	NM_001025158.2; NM_001025159.2; NM_004355.3
Protein accession_num	NP_001020329.1; NP_001020330.1; NP_004346.1
Protein name	HLA class II histocompatibility antigen gamma chain
Clonality	Monoclonal
Purification	Purified
Immunogen	Activated C57BL/6 mouse spleen cells
Manufacturer - Specificity	The rat monoclonal antibody M5/114 reacts with murine MHC class II glycoproteins. It recognizes a shared determinant on I-Ab, I-Ad, I-Aq, and I-Ed, I-Ek alloantigens, but it does not react with I-Af, I-Ak, I-As. This antibody can inhibit I-A-restricted T cell responses of the H-2b, H-2d, H-2q, H-2u but not H-2f, H-2k, H-2s haplotypes.
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg (C100)

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Delivery expected until 1/8/2026

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