RELA Antibody (OACA02434)

transcription factor p65

60 kDa

5970

NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Caprylic Acid Ammonium Sulfate Precipitation purified

Provided in PBS, pH 7.4, 50% Glycerol, 0.03% Proclin 300

Wet Ice