ULK3 Antibody (OACA08396)

Item no.	OACA08396
Manufacturer	AVIVA Systems Biology
Amount	50ul
Category	Antibodies Cell Biology Cell Status Immunohistochemistry Autophagy Primary Antibodies
Type	Antibody Polyclonal
Applications	IHC
Specific against	other
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Gene symbol	ULK3
Protein name	Serine/threonine-protein kinase ULK3
Product format	Liquid
Gene id	25989
Reconstitution and storage	Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
Description of target	Serine/threonine protein kinase that acts as a regulator of Sonic hedgehog (SHH) signaling and autophagy. Acts as a negative regulator of SHH signaling in the absence of SHH ligand: interacts with SUFU, thereby inactivating the protein kinase activity and preventing phosphorylation of GLI proteins (GLI1, GLI2 and/or GLI3). Positively regulates SHH signaling in the presence of SHH: dissociates from SUFU, autophosphorylates and mediates phosphorylation of GLI2, activating it and promoting its nuclear translocation. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently. Also acts as a regulator of autophagy: following cellular senescence, able to induce autophagy.
Purification	Antigen Affinity Purified
Clonality	Polyclonal
Formulation	PBS with, 50% glycerol, pH7.3.
Immunogen	Recombinant human Serine/threonine-protein kinase ULK3 protein (44-240AA)
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ul

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Delivery expected until 10/9/2025

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