Comparison

ERLIN2 Antibody (OACA08617)

Item no. OACA08617
Manufacturer AVIVA Systems Biology
Amount 50ul
Category
Type Antibody Polyclonal
Applications WB, IHC
Specific against other
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Gene symbol
ERLIN2
Protein name
Erlin-2
Product format
Liquid
Gene id
11160
Reconstitution and storage
Shipped at 4C. Upon delivery aliquot and store at -20C or -80C. Avoid repeated freeze.
Description of target
Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1, 4, 5-trisphosphate receptors (IP3Rs) such as ITPR1. Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex.
Purification
Antigen Affinity Purified
Clonality
Polyclonal
Formulation
PBS with, 50% glycerol, pH7.3.
Immunogen
Recombinant human Erlin-2 protein (212-339AA)
Drywet
Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 50ul
Available: In stock
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