Comparison

DKK4 Antibody (OACD03063)

Item no. OACD03063
Manufacturer AVIVA Systems Biology
Amount 100ul
Category
Type Antibody Polyclonal
Applications WB, IHC, ICC, IHC-P
Specific against other
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Available
Protein name
Dickkopf-related protein 4
Molecular weight
25 kDa
Product format
Liquid
Gene id
27121
Reconstitution and storage
Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.
Description of target
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
Purification
Antigen-specific affinity chromatography
Clonality
Polyclonal
Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol
Immunogen
Range: Gln107 - His212
Drywet
Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ul
Available: In stock
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