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IL-23 Antibody (OADB00347)

IL-23 Antibody (OADB00347)

Manufacturer	AVIVA Systems Biology
Category	Antibodies Immunohistochemistry Primary Antibodies Neutralization
Type	Antibody Monoclonal
Specific against	other
Isotype	IgG1
Applications	IHC-P, Neutralization
Amount	500 ug
Host	Mouse
Item no.	OADB00347
eClass 6.1	32160702
eClass 9.0	42030590
Available
Gene symbol	IL-23
Protein name	interleukin-23 subunit alpha
Molecular weight	21 kDa
Product format	Lyophilized
Gene id	51561
Reconstitution and storage	Stable at +2-8C for 12 months. For longer storage, freeze aliquots
Description of target	This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
Purification	Ion exchange chromatography
Biological activity	Neutralises the bioactivity of rhIL-23 on mouse splenocytes C57BI/6
Clonality	Monoclonal
Formulation	Phosphate-buffered saline. Sterile-filtered through 0.22 um and treated to remove endotoxins. Carrier and preservative free
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 500 ug

available

Delivery expected until 5/30/2024