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Methylcholanthrene Antibody (OADC00002)

Methylcholanthrene Antibody (OADC00002)

Item no.	OADC00002
Manufacturer	AVIVA Systems Biology
Amount	50ug
Category	Antibodies Primary Antibodies Dot Blot
Type	Antibody Polyclonal
Applications	Dot Blot
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Product format	Liquid. Provided in PBS containing 0.05% azide and 0.05% ProClin 300.
Reconstitution and storage	Store at -20C. Avoid repeated freeze/thaw cycles.
Description of target	3-methylcytosine arises by erroneous methylation of DNA through spontaneous exposure to endogenous S-adenosyl methionine (SAM). Since the N3-position in cytosine is protected in double stranded DNA, this phenomenon mainly occurs in single stranded DNA. The resulting 3-mC is toxic and mutagenic and increased levels of 3-mC seem to impair cell proliferation. Therefore, it has to be repaired by the cell. This is established by oxidative demethylation, which is catalyzed by the AlkB protein.
Homology	Mouse
Purification	Protein G purified
Clonality	Polyclonal
Conjugation	Unconjugated
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50ug

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Delivery expected until 8/28/2025

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