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RAD50 Antibody - N-terminal region (OAGA06330)

RAD50 Antibody - N-terminal region (OAGA06330)

Manufacturer	AVIVA Systems Biology
Category	Antibodies Immunohistochemistry Immunoprecipitation Western Blot Primary Antibodies Immunoblot
Type	Antibody Polyclonal
Specific against	other
Isotype	IgG
Applications	WB, IP, IHC-P, Immunoblot
Amount	100 ul
Host	Rabbit
Item no.	OAGA06330
eClass 6.1	32160702
eClass 9.0	32160702
Available
Gene symbol	RAD50
Protein name	DNA repair protein RAD50
Product format	Liquid
Gene id	10111
Reconstitution and storage	Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Description of target	The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.
Purification	Purified by antigen-affinity chromatography.
Clonality	Polyclonal
Immunogen	Recombinant protein encompassing a sequence within the N-terminus region of human Rad50. The exact sequence is proprietary.
Drywet	Wet Ice

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

available

Delivery expected until 5/30/2024