Comparison

TET1 Antibody (OAGA08281)

Item no. OAGA08281
Manufacturer AVIVA Systems Biology
Amount 100 ul
Category
Type Antibody Monoclonal
Applications WB, IF, IP, IHC, ICC, ChIP
Specific against other
Host Mouse
Isotype IgG2a
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Available
Gene symbol
TET1
Protein name
methylcytosine dioxygenase TET1
Molecular weight
235 kDa
Product format
Liquid PBS
Gene id
80312
Reconstitution and storage
Store as a concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze/thaw cycles.
Description of target
Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.
Purification
Affinity purified by Protein G.
Clonality
Monoclonal
Immunogen
Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.
Drywet
Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ul
Available: In stock
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