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SARS-CoV Spike Antibody

SARS-CoV Spike Antibody

Item no.	OAPB00218
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies ELISA Cardiovascular Research Heart Failure Myocardial Infarction Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	ELISA
Specific against	Virus, SARS-CoV-2, Coronavirus
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	Marra et al. Science 2003;300:1399-404. Rota et al. Science 2003;300:1394-9. Navas-Nartin et al. J Neurovirol. 2004;10:75-85. Li et al. Nature 2003;426:450-4.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E2;Peplomer protein;sars2;spike glycoprotein.
Similar products	SARS Spike
Shipping Condition	Cool pack
Available
Specificity	SARS-CoV-2 / COVID-19 Virus, Severe Acute Respiratory Syndrome Coronavirus, Virus
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Infectious Disease, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	SARS-CoV Spike antibody can be used for the detection of SARS-CoV Spike protein in ELISA. It will detect 5 ng of free peptide at 1 ug/mL.
Gene symbol	S
Gene Fullname	spike glycoprotein
Product format	Liquid. SARS-CoV Spike antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	Stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Spike protein S1: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 and CLEC4M/DC-SIGNR receptors and internalization of the virus into the endosomes of the host cell induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.
Protein name	Spike glycoprotein
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Anti-SARS-CoV Spike antibody (3225) was raised against a peptide corresponding to 15 amino acids near the center of SARS-CoV Spike glycoprotein. The immunogen is located within amino acids 650-700 of SARS-CoV Spike.
Homology	Predicted reactivity based on immunogen sequence: SARS-CoV2 Spike protein: (identity 40%, homology 56%)
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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Delivery expected until 10/30/2025

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