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SARS-CoV-2 Envelope Antibody

SARS-CoV-2 Envelope Antibody

Item no.	OAPB00317
Manufacturer	AVIVA Systems Biology
Amount	0.1 mg
Category	Neuroscience Aging & Neurological Disorders Infectious Diseases Viral Infections Coronavirus (COVID-19) Antibodies Immunohistochemistry ELISA Immunofluorescence Primary Antibodies Immunostaining
Type	Antibody Polyclonal
Format	Liquid
Applications	IF, IHC, ELISA
Specific against	Virus, Coronavirus
Host	Rabbit
Isotype	IgG
Conjugate/Tag	Unconjugated
Citations	Gorbalenya. bioRxiv: 2020. Hui et al. Int J Infect Dis. 2020;91:264-266. Pervushin et al. PLoS Pathog. 2009; 5(7): e1000511.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	envelope protein;GU280_gp04.
Similar products	SARS Envelope
Shipping Condition	Cool pack
Available
Specificity	Severe Acute Respiratory Syndrome Coronavirus, Virus
Manufacturer - Type	Polyclonal Antibody
Manufacturer - Category	Root Catalog/Products/Polyclonal Antibodies, Root Catalog/Products/Polyclonal Antibodies/Infectious Disease, Root Catalog/Products/Primary Antibodies
Shipping Temperature	Wet Ice
Manufacturer - Application Additional Information	IHC/IF: 2-3 ug/mL Antibody validated in IHC and IF in COVID-19 patient samples. SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody can detect 50 ng of free peptide at 1 ug/mL in ELISA. But it cannot detect envelope recombinant protein in WB and ELISA.
Gene symbol	E
Gene Fullname	envelope protein
Product format	Liquid. SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope Antibody is supplied in PBS containing 0.02% sodium azide.
Reconstitution and storage	Stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Description of target	Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019â€“20 coronavirus outbreak. The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. Envelope protein is a small polypeptide that contains at least one alpha-helical transmembrane domain. It involves in several aspects of the virus's life cycle, such as assembly, budding, envelope formation, and pathogenesis. E protein has membrane permeabilizing activity, which provides a possible rationale to inhibit in vitro ion channel activity of some synthetic coronavirus E proteins, and also viral replication.
Protein accession_num	https://www.ncbi.nlm.nih.gov/protein/QHD43418
Protein name	envelope protein [Severe acute respiratory syndrome coronavirus 2]
Clonality	Polyclonal
Purification	Affinity Purified
Immunogen	Anti-SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope antibody (3531) was raised against a peptide corresponding to 10 amino acids near the amino terminus of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope protein. The immunogen is located within the first 50 amino acids of SARS-CoV-2 (COVID-19, 2019-nCoV) Envelope.
Homology	SARS-CoV Envelope proteins: (100%)
Concentration	1 mg/ml

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 0.1 mg

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