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Human CD11b/Mac-1a Antibody : Biotin (OASB01037)

Human CD11b/Mac-1a Antibody : Biotin (OASB01037)

Item no.	OASB01037
Manufacturer	AVIVA Systems Biology
Amount	100 tests
Category	Neuroscience Neural Lineage Markers Neuroinflammation Aging & Neurological Disorders Antibodies Primary Antibodies Oligodendrocyte Markers
Type	Antibody Monoclonal
Format	Biotin (BIOT) Conjugate
Clone	ICRF44
Specific against	other
Host	Mouse
Isotype	IgG1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Available
Gene symbol	ITGAM
Protein name	integrin alpha-M
Gene id	3684; 397459; 714832; 101866035; 454069; 101004087
Reconstitution and storage	Store at 2-8C
Description of target	This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (' Mac-1' ), or inactivated-C3b (iC3b) receptor 3 (' CR3' ). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Monoclonal
Conjugation	Biotin
Warning	Reagents contain sodium azide which is very toxic if ingested or inhaled. Avoid contact with skin, eyes, orclothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copiousamounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxichydrazoic acid under acidic conditions. Dilute azide- containing compounds in running water beforediscarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Dilution	Flow Cytometry: Purified (UNLB) antibody Biotin conjugate R-phycoerythrin conjugate Allophycocyanin conjugate Spectral Red conjugate AF647 conjugate <= 1 ug/10⁶ cells 10 uL/10⁶ cells 10 uL/10⁶ cells 10 uL/10⁶ cells 10 uL/10⁶ cells 10 uL/10⁶ cells
Immunogen	Rheumatoid synovial cells and human monocytes
Drywet	Wet Ice

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 tests

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Delivery expected until 8/28/2025

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