SELPLG ELISA Kit (Mouse) (OKCD00263)

P-selectin glycoprotein ligand 1

20345

A SLe(x)-type proteoglycan, which through high affinity, calcium-dependent interactions with E- and P-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation. Critical for the initial leukocyte capture.3 Publications < p>Manually curated information for which there is published experimental evidence.< /p> < p>< a href="/manual/evidences#ECO:0000269">Moreâa‚¬A< /a>< /p> Manual assertion based on experiment iniRef.3"P-Selectin glycoprotein ligand 1 (PSGL-1) is a physiological ligand for E-selectin in mediating T helper 1 lymphocyte migration."_x005F_x000D_ Hirata T., Merrill-Skoloff G., Aab M., Yang J., Furie B.C., Furie B._x005F_x000D_ J. Exp. Med. 192:1669-1676(2000) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH SELE AND SELP, FUNCTION.Ref.4"P-, E-, and L-selectin mediate migration of activated CD8+ T lymphocytes into inflamed skin."_x005F_x000D_ Hirata T., Furie B.C., Furie B._x005F_x000D_ J. Immunol. 169:4307-4313(2002) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.Ref.6"Complete identification of E-selectin ligands on neutrophils reveals distinct functions of PSGL-1, ESL-1, and CD44."_x005F_x000D_ Hidalgo A., Peired A.J., Wild M.K., Vestweber D., Frenette P.S._x005F_x000D_ Immunity 26:477-489(2007) [PubMed] [Europe PMC] [Abstract]Cited for: FUNCTION.

< 0.066 ng/mL