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Nr1h3 Peptide - C-terminal region (AAP32674)

Nr1h3 Peptide - C-terminal region (AAP32674)

Item no.	AAP32674
Manufacturer	AVIVA Systems Biology
Amount	100ug
Category	Neuroscience Metabolism Cholesterol & Lipid Metabolism Targets for Rodent Neurosciences Peptides & Proteins Western Blot Peptides
Type	Peptides
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AU018371, LXR, RLD1, Unr1
Similar products	Nr1h3
Available
Description	This is a synthetic peptide designed for use in combination with anti-Nr1h3 Antibody (ARP32674_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	Nr1h3
Protein size	445
Molecular weight	50kDa
Product format	Lyophilized powder
Gene id	22259
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins	Ppargc1a, Ppargc1b, Ppargc1a, Ppargc1b, Rxra, Rxrg, Ubc, Zfp111
Description of target	Nr1h3 is an orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Nr1h3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AAP32674-datasheet.pdf

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Amount: 100ug

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Delivery expected until 9/25/2025

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