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FOXO4 Peptide - C-terminal region (AAP32110)

FOXO4 Peptide - C-terminal region (AAP32110)

Item no.	AAP32110
Manufacturer	AVIVA Systems Biology
Amount	100ug
Category	Oncology Neuroscience Metabolism Diabetes Cholesterol & Lipid Metabolism Regulation of Appetite Molecular Targets for Neuroscience Targets for Rodent Neurosciences Aging & Neurological Disorders Neural Adhesion Molecules Peptides & Proteins Western Blot Peptides By Organ Skin Cancer
Type	Peptides
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AFX, AFX1, MGC120490, MLLT7
Similar products	FOXO4
Available
Description	This is a synthetic peptide designed for use in combination with anti-FOXO4 Antibody(ARP32110_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	FOXO4
Protein size	505
Molecular weight	54kDa
Product format	Lyophilized powder
Gene id	4303
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins	AKT1, CCND1, CDKN1A, CTNNB1, FOXG1, SMAD3, SMAD4, AKT1, AKT2, CREBBP, CTNNB1, ESR1, FOXG1, SMAD3, SMAD4, XPO1, YWHAZ, CREBBP, CTNNB1, ESR1, MDM2, PIN1, SMAD3, SMAD4, UBC, USP7, XPO1
Description of target	FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100ug

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Delivery expected until 9/11/2025

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