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SIN3B Peptide (AAP50589)

SIN3B Peptide (AAP50589)

Item no.	AAP50589
Manufacturer	AVIVA Systems Biology
Amount	100 ug
Category	Neuroscience Neural Lineage Markers Metabolism Glucose Homeostasis Aging & Neurological Disorders Neural Epigenetics Peptides & Proteins Western Blot Peptides Glial Cell Markers
Type	Peptides
Format	Lyophilized powder
Applications	WB
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	KIAA0700
Similar products	SIN3B
Available
Description	This is a synthetic peptide designed for use in combination with anti-SIN3B antibody (Catalog #: ARP50589_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	SIN3B
Protein size	1162
Molecular weight	133kDa
Product format	Lyophilized powder
Gene id	23309
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins	HDAC1, HDAC9, IKZF1, IKZF4, MAD1L1, MXD1, MXI1, REST, SETDB1, ZBTB16, HCFC1, HDAC1, HDAC9, IKZF1, IKZF2, IKZF3, IKZF4, MECP2, RNF220, SAP30, SETDB1, SUDS3, WHSC1, ZBTB16
Description of target	SIN3B acts as a transcriptional repressor. It interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities.It also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. SIN3B also forms a complex with FOXK1 which represses transcription.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AAP50589-datasheet.pdf

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Amount: 100 ug

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Delivery expected until 10/9/2025

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