Comparison

PRKCI Peptide - middle region (AAP56427)

Item no. AAP56427
Manufacturer AVIVA Systems Biology
Amount 100ug
Category
Type Peptides
Format Lyophilized powder
Applications WB
Specific against Human (Homo sapiens)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias DXS1179E, MGC26534, PKCI, nPKC-iota
Similar products PRKCI
Available
Description
This is a synthetic peptide designed for use in combination with anti-PRKCI Antibody(ARP56427_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol
PRKCI
Protein size
596
Molecular weight
68kDa
Product format
Lyophilized powder
Gene id
5584
Reconstitution and storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Partner proteins
PAWR, SMG1, FRS3, MBP, SELL, SQSTM1, ADAP1, ANXA1, CDC42, CHUK, FRS2, FRS3, GAPDH, HRAS, IRAK1, MAP2K1, MAP2K5, MARK4, MBP, NFKBIA, PARD3, PARD6A, PARD6B, PARD6G, PDPK1, PNMA1, RAB2A, RAB4A, RAC1, RHOQ, SMG1, SQSTM1, SRC, USP20, YWHAH, YWHAZ, ADAP1, BAD, FRS2, Frs2, GABARAPL1, GABARAPL2, GAPDH, MA
Description of target
This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ug
Available: In stock
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