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PTPN21 Peptide - C-terminal region (AAP65819)

PTPN21 Peptide - C-terminal region (AAP65819)

Item no.	AAP65819
Manufacturer	AVIVA Systems Biology
Amount	100ug
Category	Oncology Neuroscience Neural Lineage Markers Neural Transcription Factors Peptides & Proteins Western Blot Peptides By Organ Colorectal Cancer
Type	Peptides
Format	Lyophilized powder
Applications	WB
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	PTPD1, PTPRL10
Similar products	PTPN21
Available
Description	This is a synthetic peptide designed for use in combination with anti-PTPN21 Antibody (ARP65819_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Gene symbol	PTPN21
Protein size	1174
Molecular weight	133kDa
Product format	Lyophilized powder
Gene id	11099
Reconstitution and storage	Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Description of target	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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AAP65819-datasheet.pdf

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Amount: 100ug

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Delivery expected until 10/30/2025

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