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TOPBP1 Recombinant Protein (OPCD00180)

TOPBP1 Recombinant Protein (OPCD00180)

Item no.	OPCD00180
Manufacturer	AVIVA Systems Biology
Amount	10ug
Category	Peptides & Proteins Recombinant Proteins Immunoprecipitation Western Blot ELISA SDS-PAGE
Type	Proteins Recombinant
Applications	WB, IP, ELISA, SDS-PAGE
Specific against	other
Host	E.coli
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Gene symbol	TOPBP1
Protein name	DNA topoisomerase 2-binding protein 1
Molecular weight	32 kDa
Product format	Lyophilized
Gene id	235559
Reconstitution and storage	Reconstitute in PBS or others. Store at 2-8C for one month. Aliquot and store at -80C for 12 months. Avoid repeated freeze/thaw cycles.
Description of target	Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control . Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR.
Conjugation	Unconjugated
Formulation	PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Purity	> 90%

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPCD00180-datasheet.pdf

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Amount: 10ug

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Delivery expected until 10/9/2025

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