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EZH1 Recombinant Protein (OPCD00861)

EZH1 Recombinant Protein (OPCD00861)

Item no.	OPCD00861
Manufacturer	AVIVA Systems Biology
Amount	10ug
Category	Peptides & Proteins Recombinant Proteins Western Blot SDS-PAGE
Type	Proteins Recombinant
Applications	WB, SDS-PAGE
Specific against	other
Host	E.coli
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Gene symbol	EZH1
Protein name	Histone-lysine N-methyltransferase EZH1
Molecular weight	25 kDa
Product format	Lyophilized 100mM NaHCO₃, 500mM NaCl (pH 8.3), containing 1mM DTT, 0.01% SKL, 5% Trehalose & Proclin300 Physical Appearance: Freeze-dried powder
Gene id	2145
Reconstitution and storage	Reconstitute in 100mM NaHCO₃, 500mM NaCl (pH 8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex. Store at 2-8C for one month. Aliquot and store at -80C for 12 months. Avoid repeated freeze/thaw cycles.
Description of target	Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation.
Conjugation	Unconjugated
Formulation	100mMNaHCO3, 500mMNaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Purity	> 95%

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPCD00861-datasheet.pdf

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Amount: 10ug

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Delivery expected until 10/9/2025

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