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CYP3A4 Recombinant Protein (OPCD02620)

CYP3A4 Recombinant Protein (OPCD02620)

Item no.	OPCD02620
Manufacturer	AVIVA Systems Biology
Amount	10ug
Category	Peptides & Proteins Recombinant Proteins Western Blot SDS-PAGE
Type	Proteins Recombinant
Applications	WB, SDS-PAGE, other
Specific against	other
Host	E.coli
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Available
Gene symbol	CYP3A4
Protein name	Cytochrome P450 3A4
Molecular weight	22 kDa
Product format	Lyophilized from 20mM Tris, 150mM NaCl, pH 8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300
Gene id	1576
Reconstitution and storage	Reconstitute in 20mM Tris, 150mM NaCl, pH 8.0 to a concentration of 0.1-1.0 mg/ml. Do not vortex. Store at 2-8° C for one month. Aliquot and store at -80° C for 12 months. Avoid repeated freeze/thaw cycles.
Description of target	Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1, 8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide. Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro. Catalyzes sulfoxidation of the anthelmintics albendazole and fenbendazole.
Purity	> 90%

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPCD02620-datasheet.pdf

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Delivery expected until 10/9/2025

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