Comparison

GZMA Recombinant Protein (OPCD08056)

Item no. OPCD08056
Manufacturer AVIVA Systems Biology
Amount 10ug
Category
Type Proteins Recombinant
Applications WB, IP, ELISA, SDS-PAGE
Specific against other
Host Yeast
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Available
Gene symbol
GZMA
Protein name
Granzyme A
Molecular weight
28 kDa
Product format
Lyophilized
Gene id
3001
Reconstitution and storage
Reconstitute in PBS or others.
Store at 2-8C for one month. Aliquot and store at -80C for 12 months. Avoid repeated freeze/thaw cycles.
Description of target
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
Conjugation
Unconjugated
Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
Purity
> 95%

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 10ug
Available: In stock
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