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GLP1 Protein (OPPA01049)

GLP1 Protein (OPPA01049)

Manufacturer	AVIVA Systems Biology
Category	Metabolism Diabetes Glucose Homeostasis Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	other
Format	The GLP-1 peptide was lyophilized with no additives. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Amount	1mg
Item no.	OPPA01049
eClass 6.1	34160400
eClass 9.0	42020190
Available
Gene symbol	GLP1
Protein name	Glucagon Like Peptide-1
Molecular weight	3 kDa
Product format	Lyophilized with no additives. Physical appearance: Sterile filtered white powder.
Gene id	2641
Reconstitution and storage	It is recommended to reconstitute the lyophilized Glucagon Like Peptide-1 in sterile 20mM AcOH at 1mg/ml, which can then be further diluted to other aqueous solutions. Lyophilized Glucagon Like Peptide-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution GLP-1 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
Description of target	Glucagon-like peptide-1 (GLP-1) is derived from the transcription product of the proglucagon gene. The major source of GLP-1 in the body is the intestinal L cell that secretes GLP-1 as a guthormone. The biologically active forms of GLP-1 are: GLP-1-(7-37) and GLP-1-(7-36)NH2. GLP-1 secretion by L cells is dependent on the presence of nutrients in the lumen of the small intestine. The secretagogues (agents that causes or stimulates secretion) of this hormone include major nutrients like carbohydrate, proteinand lipid. Once in the circulation, GLP-1 has a half life of less than 2 minutes, due to rapid degradation by the enzyme dipeptidyl peptidase-4.GLP-1 possesses several physiological properties that make it a subject of intensive investigation as a potential treatment of diabetes mellitus. The known physiological functions of GLP-1 include: Increases insulin secretion from the pancreas in a glucose-dependent manner, decreases glucagon secretion from the pancreas, increases beta cells mass and insulin gene expression, inhibits acid secretion and gastric emptying in the stomach, decreases food intake by increasing satiety.
Purification	The GLP-1 is purified by proprietary chromatographic techniques.
Purity	Greater than 96.0% as determined by Analysis by RP-HPLC.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 1mg

available

Delivery expected until 6/13/2024