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TIE2 Fc Protein (OPPA01161)

TIE2 Fc Protein (OPPA01161)

Item no.	OPPA01161
Manufacturer	AVIVA Systems Biology
Amount	2ug
Category	Oncology Neuroscience Molecular Targets for Neuroscience Protein Aggregation, Clearance & Misfolding By Cell Type Carcinoma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Recombinant Proteins Adenocarcinoma By Organ Heart & Blood Cancer
Type	Proteins
Format	TIE-2 Fc Chimera was lyophilized from a concentrated (1 mg/ml) sterile solution containing 1x PBS. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Specific against	other
Host	Insect cells
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Angiopoietin-1 receptor precursor, Tyrosine-protein kinase receptor TIE-2, hTIE2, Tyrosine-protein kinase receptor TEK, p140 TEK, Tunica interna endothelial cell kinase, CD202b, VMCM, VMCM1, TIE2, TIE2 Fc Human, TIE2 Fc Chimera Human Recombinant
Similar products	TIE-2 Fc
Available
Gene symbol	TIE-2 Fc
Protein name	Angiopoietin-1 receptor
Product format	TIE-2 Fc Chimera was lyophilized from a concentrated (1 mg/ml) sterile solution containing 1x PBS. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Gene id	7010
Reconstitution and storage	Reconstitution: It is recommended to reconstitute the lyophilized TIE-2 Fc Chimera in sterile water not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Storage: Lyophilized sTIE-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution TIE-2 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
Description of target	Soluble TIE-2 Human Recombinant fused with the Fc part of human IgG1 produced in baculovirus is a monomeric, glycosylated, polypeptide containing 730 amino acids and having a total molecular mass of 250 kDa. Human TIE-2/Fc monomer has a calculated molecular mass of approximately 125 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 140 kDa protein in SDS-PAGE under reducing conditions.The TIE2 Fc Chimera is purified by proprietary chromatographic techniques.
Biological activity	Measured in a functional ELISA assay. When TIE-2/Fc is immobilized at 4 ug/mL (100 ul/well), it binds rh Angiopoietin-2 with a linear range of 2-100 ng/ml.
Purity	Greater than 90.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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OPPA01161-datasheet.pdf

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Amount: 2ug

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Delivery expected until 7/24/2025