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CD14 Protein (OPPA01422)

CD14 Protein (OPPA01422)

Manufacturer	AVIVA Systems Biology
Category	Neuroscience Neuroinflammation Peptides & Proteins Recombinant Proteins
Type	Proteins
Specific against	other
Format	CD14 was lyophilized from a concentrated protein solution (1.6 mg/ml) containing phosphate-buffered saline, pH 7.2. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Amount	10ug
Host	Hamster
Item no.	OPPA01422
eClass 6.1	34160400
eClass 9.0	42020190
Available
Gene symbol	CD14-CHO
Protein name	Monocyte differentiation antigen CD14
Product format	CD14 was lyophilized from a concentrated protein solution (1.0 mg/ml) containing phosphate-buffered saline, pH 7.2. Physical appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Gene id	929
Reconstitution and storage	Reconstitution: It is recommended to reconstitute the lyophilized CD14 in sterile 18M Omega -cm H2O not less than 100 ug/ml. Further dilutions should be made with phosphate buffered saline (PBS). Storage: Lyophilized CD14 although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution CD14 should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0. 1% HSA or BSA). Please prevent freeze-thaw cycles.
Description of target	CD14 (also known lipopolysaccharide (LPS) receptor) is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. CD14 has been shown to bind apoptotic cells.
Biological activity	Up to 20 ug/ml CD14 inhibit binding of FITC-LPS (0.5 ug/ml) to 600, 000 CD14+CHO transfectants (FACS).
Purity	Greater than 95.0% as determined by SDS-PAGE.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 10ug

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Delivery expected until 5/30/2024