Comparison

Cleaved-MMP-14 (Y112) Polyclonal Antibody

Item no. BT-AP01946
Manufacturer Bioassay Technology Laboratory
Amount 20 ul
Category
Type Antibody Polyclonal
Applications WB, ELISA
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias MMP14; Matrix metalloproteinase-14; MMP-14; MMP-X1; Membrane-type matrix metalloproteinase 1; MT-MMP 1; MTMMP1; Membrane-type-1 matrix metalloproteinase; MT1-MMP; MT1MMP
Available
Ab type
Primary antibody
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by MMP14 is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. Matrix metallopeptidase 14 activates MMP2 protein, and this activity may be involved in tumor invasion.
Clonality
Polyclonal
Concentration
1 mg/ml
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP14. AA range:93-142
MolecularWeight_Da
65884
Reactivity
Human; Mouse; Rat
Storage Stability
-20°C for one year

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ul
Available: In stock
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