Comparison

Cleaved-Notch 1 (V1754) Polyclonal Antibody

Item no. BT-AP01953
Manufacturer Bioassay Technology Laboratory
Amount 20 ul
Category
Type Antibody Polyclonal
Applications WB, IF, IHC, ELISA
Specific against other
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias NOTCH1; TAN1; Neurogenic locus notch homolog protein 1; Notch 1; hN1; Translocation-associated notch protein TAN-1
Available
Ab type
Primary antibody
Background
NOTCH1 encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types. Notch signaling is an evolutionarily conserved intercellular signaling pathway that regulates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor plays a role in the development of numerous cell and tissue types. Mutations in NOTCH1 are associated with aortic valve disease, Adams-Oliver syndrome, T-cell acute lymphoblastic leukemia, chronic lymphocytic leukemia, and head and neck squamous cell carcinoma.
Clonality
Polyclonal
Concentration
1 mg/ml
Immunogen
The antiserum was produced against synthesized peptide derived from human Notch 1. AA range:1735-1784
MolecularWeight_Da
272500
Reactivity
Human; Mouse; Rat
Storage Stability
-20°C for one year

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 20 ul
Available: In stock
available

Delivery expected until 7/17/2025 

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