Tyk 2(Phospho Tyr292) Rabbit Polyclonal Antibody

This gene encodes a member of the tyrosine kinase and| more specifically| the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such| it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.

1 mg/ml

130570

-20°C for 1 year