MYH Polyclonal Antibody

MUTYH encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7, 8-dihydroguanine, a major oxidatively damaged DNA lesion. A/G-specific adenine DNA glycosylase is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

1 mg/ml

60069

-20°C for one year