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PUMA Polyclonal Antibody

PUMA Polyclonal Antibody

Item no.	BT-AP07510
Manufacturer	Bioassay Technology Laboratory
Amount	20 ul
Category	Antibodies Cell Biology Cell Status Apoptosis Western Blot ELISA Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, ELISA
Specific against	other
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	BBC3; PUMA; Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis
Available
Ab type	Primary antibody
Background	BBC3 encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. BCL2 binding component 3 cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, BBC3 is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.
Clonality	Polyclonal
Concentration	1 mg/ml
Immunogen	The antiserum was produced against synthesized peptide derived from human PUMA. AA range:120-169
MolecularWeight_Da	20532/14459
Reactivity	Human; Mouse; Rat
Storage Stability	-20°C for one year

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 20 ul

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Delivery expected until 8/14/2025

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