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Sisunatovir (hydrochloride)

Sisunatovir (hydrochloride)

Item no.	HY-123475A-10mM
Manufacturer	MedChem Express
CASRN	1903763-83-6
Amount	10 mM/1 mL
Quantity options	100 mg 10 mM/1 mL 10 mg 1 mg 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Biochemicals
Specific against	other
Purity	98.61
Citations	[1]Cockerill GS, et al. Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion. J Med Chem. 2021 Apr 8;64(7):3658-3676.
Smiles	O=C(N(C1=C2C=CC(F)=C1)CC3=NC4=CC(CN)=CC=C4N3CCCC(F)(F)F)C52CC5.[H]Cl
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	RV521 (hydrochloride)
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	COVID-19-anti-virus
Manufacturer - Targets	RSV
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, sealed storage, away from moisture)
Molecular Weight	482.90
Product Description	Sisunatovir (RV521) hydrochloride is a potent and orally active respiratory syncytial virus (RSV) inhibitor with IC50 values of 1.4, 1.0 nM for RSV A, RSV B, respectively. Sisunatovir hydrochloride inhibits RSV infection and reduces virus titers in the lungs of mice[1].
Manufacturer - Research Area	Infection
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Clinical information	Phase 3

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HY-123475A-10mM-safety-datasheet.pdf