« Back
Home /
Anti-Mouse CD4 APC-Cyanine7

Anti-Mouse CD4 APC-Cyanine7

Item no.	06122-87-25
Manufacturer	BioGems
Amount	25 ug
Category	Oncology Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies Flow Cytometry Primary Antibodies By Organ Colorectal Cancer
Type	Antibody
Format	APC-Cy7
Applications	FC
Clone	RM4-5
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Isotype	IgG2a Kappa
Conjugate/Tag	APC
Citations	Shevach, E. M. (2000). Regulatory T cells in autoimmmunity. Annual review of immunology, 18(1), 423-449. Wu, L., Scollay, R., Egerton, M., Pearse, M., Spangrude, G. J., & Shortman, K. (1991). CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus. Bliss, S. K., Bliss, S. P., Beiting, D. P., Alcaraz, A., & Appleton, J. A. (2007). IL-10 regulates movement of intestinally derived CD4+ T cells to the liver. The Journal of Immunology, 178*(12), 7974-7983.
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Available
Description	The RM4-5 monoclonal antibody specifically reacts with mouse CD4, also known as L3T4, a 55 kDa differentiation antigen expressed by the majority of thymocytes, subpopulations of mature T cells (like major histocompatibility complex class II-restricted T lymphocytes), a subset of natural killer T cells, and on pluripotent hematopoietic stem cells. CD4 binds to the major histocompatibility complex class II (MHC class II) and enhances T lymphocyte development and mature T cells functions. In T lymphocytes, CD4 binds to the cytoplasmic tail of enzyme tyrosine kinase (p56lck). Binding of RM4-5 is blocked by the anti-mouse CD4 clone GK1.5.
Storage Temperature	4C
Formulation	Phosphate-buffered aqueous solution, ≤ 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Preperation	The product should be stored undiluted at 4C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Interest	Adaptive Immunity

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

06122-87-25-datasheet.pdf

06122-87-25-safety-datasheet.pdf